| Titre : | Targeting Oral Cancer |  | Type de document :  | texte imprimé |  | Auteurs :  | Andrew Fribley, Editeur (scientifique) |  | Editeur : | Springer-Verlag |  | Année de publication :  | 2016 |  | Importance :  | 302 p. |  | ISBN/ISSN/EAN :  | 978-3-319-27645-8 |  | Langues : | Anglais (eng) |  | Résumé :  | This book provides research-oriented care providers with up-to-date information on the oral cancer patient population, the ways in which we are treating them, and the scientific approaches being pursued in order to improve survival and reduce treatment-related morbidity. The text is organized into three sections covering epidemiology and management, cancer development and biomarkers, and breaking developments and novel approaches for drug discovery. The first section includes discussion of the emerging role of HPV in oral cancer and explains the surgical, chemotherapy and radiation approaches to treatment. Aspects such as molecular progression, the role of cancer stem cells in tumor development, and the value of various biomarkers are then examined. The final section is devoted to the latest advances and covers, among other topics, current clinical trials, emerging drug targets, and targeting of the unfolded protein response and of mediators of coagulation. |  | Note de contenu :  | Table of contents (12 chapters) 
Assessing the Changing Oral and Pharyngeal Cancer Demographic in the United States 
 
Holpuch, Andrew S. (et al.) 
 
Pages 3-19 
Preview Buy Chapter $29.95 
The Emerging Role of HPV in Head and Neck Cancer 
 
Carey, Thomas E. 
 
Pages 21-36 
Oral Cancer: Location, Staging, Surgical Management, and Outcomes 
 
Chen, Michael Z. (et al.) 
 
Pages 37-52 
Chemotherapy in Head and Neck Squamous Cell Cancer 
 
Burchhardt, Daniela M. (et al.) 
 
Pages 53-68 
Molecular Signaling in Oral Cancer Invasion and Metastasis 
 
Chang, Insoon (et al.) 
 
Pages 71-99 
Cancer Stem Cells in the Biology and Treatment of Head and Neck Squamous Cell Carcinoma 
 
Kim, Hong S. (et al.) 
 
Pages 101-113 
HNSCC Biomarkers Derived from Key Processes of Cancerogenesis 
 
Raudenska, Martina (et al.) 
 
Pages 115-160 
Emerging Molecular Targets in the Treatment of Head and Neck Squamous Cell Carcinoma 
 
Warner, Blake M. (et al.) 
 
Pages 163-209 
Immunotherapy in Head and Neck Cancers 
 
Feng, Zipei (et al.) 
 
Pages 211-224 
The Unfolded Protein Response as a Therapeutic Target for Head and Neck Squamous Cell Carcinoma 
 
Garshott, Danielle M. (et al.) 
 
Pages 225-261 
Targeting Coagulation Mediators in Head and Neck Cancer 
 
Jesudas, Rohith (et al.) 
 
Pages 263-281 
Mucosal Therapy for Potentially Malignant Diseases and OSCC 
 
Svider, Peter F. (et al.) 
 
Pages 283-299 |   
 
  			Targeting Oral Cancer [texte imprimĂ©] /  Andrew Fribley, Editeur (scientifique) . -  [S.l.] : Springer-Verlag, 2016 . - 302 p.. ISBN : 978-3-319-27645-8 Langues : Anglais ( eng) | RĂ©sumĂ© :  | This book provides research-oriented care providers with up-to-date information on the oral cancer patient population, the ways in which we are treating them, and the scientific approaches being pursued in order to improve survival and reduce treatment-related morbidity. The text is organized into three sections covering epidemiology and management, cancer development and biomarkers, and breaking developments and novel approaches for drug discovery. The first section includes discussion of the emerging role of HPV in oral cancer and explains the surgical, chemotherapy and radiation approaches to treatment. Aspects such as molecular progression, the role of cancer stem cells in tumor development, and the value of various biomarkers are then examined. The final section is devoted to the latest advances and covers, among other topics, current clinical trials, emerging drug targets, and targeting of the unfolded protein response and of mediators of coagulation. |  | Note de contenu :  | Table of contents (12 chapters) 
Assessing the Changing Oral and Pharyngeal Cancer Demographic in the United States 
 
Holpuch, Andrew S. (et al.) 
 
Pages 3-19 
Preview Buy Chapter $29.95 
The Emerging Role of HPV in Head and Neck Cancer 
 
Carey, Thomas E. 
 
Pages 21-36 
Oral Cancer: Location, Staging, Surgical Management, and Outcomes 
 
Chen, Michael Z. (et al.) 
 
Pages 37-52 
Chemotherapy in Head and Neck Squamous Cell Cancer 
 
Burchhardt, Daniela M. (et al.) 
 
Pages 53-68 
Molecular Signaling in Oral Cancer Invasion and Metastasis 
 
Chang, Insoon (et al.) 
 
Pages 71-99 
Cancer Stem Cells in the Biology and Treatment of Head and Neck Squamous Cell Carcinoma 
 
Kim, Hong S. (et al.) 
 
Pages 101-113 
HNSCC Biomarkers Derived from Key Processes of Cancerogenesis 
 
Raudenska, Martina (et al.) 
 
Pages 115-160 
Emerging Molecular Targets in the Treatment of Head and Neck Squamous Cell Carcinoma 
 
Warner, Blake M. (et al.) 
 
Pages 163-209 
Immunotherapy in Head and Neck Cancers 
 
Feng, Zipei (et al.) 
 
Pages 211-224 
The Unfolded Protein Response as a Therapeutic Target for Head and Neck Squamous Cell Carcinoma 
 
Garshott, Danielle M. (et al.) 
 
Pages 225-261 
Targeting Coagulation Mediators in Head and Neck Cancer 
 
Jesudas, Rohith (et al.) 
 
Pages 263-281 
Mucosal Therapy for Potentially Malignant Diseases and OSCC 
 
Svider, Peter F. (et al.) 
 
Pages 283-299 |  
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